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Neuro-MS/D

series of transcranial magnetic stimulators for diagnostic, therapeutic and research purposes


neuro-msd.zip
(pdf-file, 1.07 MB)


USB connection
ISO quality certificate
CE conformance certificate
Certificates of conformance to CIS requirements

FeaturesDelivery Set VariantsApplicationsDelivery SetBack to Magnetic Stimulators


  • Peak magnetic field — up to 4 Tesla
  • Number of pulses generated during one session — up to 10 000
  • Several delivery set variants
  • Cooling unit and expansion unit can be included in the delivery set optionally
  • Pulse waveform: monophasic, biphasic, theta-burst (TBS), paired stimulation
  • 2-channel digital EMG system for motor response threshold acquisition
  • Neuro-MS.NET software for magnetic stimulator control
  • Set of different coils (non-cooled, cooled, placebo)
  • "Delayed charging" mode
  • Multistage system of device protection
  • Connection to computer via USB port

Features

Modular Construction

New version of magnetic stimulator consists of several separate units, thus you can select the configuration required for you. We offer you several ready-made configuration variants that can be most conveniently applied for the practical use.

Main Unit

Main unit is the basis of any configuration. The main stimulator unit is intended for stimulator operation control and can be used as an independent device (if it is equipped with coils). The front panel contains digital indicators displaying all parameters of stimulator operation and controls used to adjust stimulation parameters.

Cooling Unit

One of the problems of magnetic stimulator application is quick overheating of coils during the stimulation performing. In Neuro-MS/D this problem is solved with the use of special cooling unit and cooled coils. In fact, this is a tank with the cooling liquid, the pump running the cooling liquid through the coil and the fridge. The unit allows increasing continuous operation time up to 10 000 pulses without overheating. Actually, it means that stimulator can operate for a long time without overheating.

Extra Power Supply Unit

The main unit of the magnetic stimulator allows operating with up to 30 Hz frequency. However, the stimulator does not generate the maximal induction at 30 Hz frequency. It can be achieved only at 5 Hz (or less) frequency. Also there is a term “maximal effective stimulation frequency”. This term indicates the frequency at which transcranial magnetic stimulation can be performed and each pulse in series is higher than motor threshold for most people. For main unit it equals 10 Hz. The extra power supply unit makes it possible to increase this frequency twice (up to 20 Hz).

Neuro-EMG-MS is a Special Device to Record Motor Evoked Potentials

This device is EMG amplifier. If you connect it to computer, you can record the motor evoked potentials obtained at TMS stimulation of motor areas of cerebral cortex and peripheral nervous system. When you record the motor evoked potentials, you can define the so called motor threshold (MT). This is a very important parameter. As far the stimulation amplitude at performing of treatment procedures is often set relative to obtained MT.

Neuro-MS.NET Software

The delivery set includes the special software for magnetic stimulator control with the use of computer. This software allows keeping the patient database, detecting motor response threshold, controlling the stimulation courses and sessions. A user can perform the stimulation according to already specified stimulation programs and also create own ones or edit the available stimulation programs.

New Coil Holder

Now Neuro-MS/D delivery set includes FISSO holder to fix the magnetic stimulator coil. It very convenient as it can be fixed in any position by rotating one screw. You can order this coil holder for other delivery set variants.

Specialized Computer

The device can be both equipped with common computer and specialized one with touchscreen interface. Neuro-MS.NET is specially adapted finger-controlled software. It allows controlling the magnetic stimulator operation quickly and conveniently.

Operation with Any Neurophysiological Equipment

Neuro-MS/D magnetic stimulator can operate jointly with neurophysiological equipment manufactured by Neurosoft Ltd. and also digital EMG systems of third-party manufacturers. To connect to EMG systems of third-party manufacturers, the trigger socket is provided. The special trigger unit can also be applied to adjust the trigger pulse parameters.

Main UnitMain Unit
Cooling UnitCooling Unit
Extra Power Supply UnitExtra Power Supply Unit

Delivery Set Variants

1st Variant: Diagnostic

The diagnostic variant of magnetic stimulator is intended first of all for joint operation with neurophysiological (EMG) equipment to study the state of cerebral, spinal and peripheral pathways.

The maximum diagnostic capabilities can be shown if the device is used together with neurophysiological digital system manufactured by Neurosoft Ltd. However, the magnetic stimulator can operate with devices of other manufacturers.

Neuro-MS/D (Diagnostic Variant) Applications:
    Neurology:
  • study of motor response at magnetic stimulation of peripheral nerves;
  • determination of central motor conduction time in patients suffering from demyelinating diseases of nervous system, in particular, multiple sclerosis;
  • assessment of excitability and flexibility of cortex motor zones;
  • assessment of root conduction time (F-wave and segmental magnetic stimulation) at osteochondrosis.
    Ophthalmology:
  • diagnostics of visual pathway defects.
    Epileptology:
  • study of epilepsy by means of noninvasive location of epileptic focuses and determination of lateralization of speech center before the brain surgery.
    Pulmonology:
  • stimulation of phrenic nerve for study of diaphragm response.

To avoid artifacts during neurophysiological responses acquisition, the stimulator provides the possibility of delayed charging of high-voltage capacitor.

The diagnostic variant can be applied partially with therapeutic purposes to perform transcranial stimulation and almost without any limits to stimulate peripheral nerves and muscles.


2nd and 3rd Variants: Therapeutic and Advanced Therapeutic

The principle of therapeutic magnetic stimulation is based on the following. The magnetic stimulator uses the magnetic pulses of short duration and emerging high-intensity electromagnetic field easily penetrates through clothes, cranium bones and soft tissues. They exert influence upon deep nerve centers, peripheral nerves, cerebral and spinal cord, which are inaccessible for other kinds of stimulation.

The distinctive feature of Neuro-MS/D device is possibility to perform transcranial magnetic stimulation (TMS). However, the well-known problem is quick coil overheating.

The cooling unit included in therapeutic delivery set variant allows performing long-term therapeutic impacts (also transcranial magnetic stimulation with high frequency and intensity) without coil overheating.

Advanced therapeutic variant provides the possibility to increase the so called maximal effective stimulation frequency (the frequency when each stimulus in series has 100% intensity of motor threshold for most people) twice (up to 20 Hz) owing to extra power supply unit.

Most often these stimulator variants are used to treat depressions (including severe and drug-resistant), tinnitus. Besides, there are positive and encouraging results obtained at rehabilitation of stroke patients.

Neuro-MS/D (Therapeutic) Applications:
    Neurology:
  • treatment of central and peripheral nervous system disorders: vascular and vertegragenic pathologies, consequences of stroke, neuropathies, demyelinating disorders of nervous system, spinocerebellar degeneration, spasticity, pain syndrome, radiculopathies, hemicrania, Alzheimer‘s disease.
    Ophthalmology:
  • partial atrophy of visual nerve owing to different etiology.
    Psychiatry:
  • treatment of depressions, schizophrenia, obsessive-compulsive disorders, manias and other psychiatric disorders.

The delivery set of therapeutic variant includes Neuro-MS.NET software allowing to program any stimulation algorithms. It also provides theta-burst mode with up to 100 Hz stimulation frequency.

In case the therapeutic variant is equipped with neurophysiological equipment, it will receive all capabilities of diagnostic variant.


TMS Use to Make Prognosis for Rehabilitation of Stroke Patients

The magnetic stimulator can be successfully used to make rehabilitation prognosis for stroke patients. At that the following parameters are studied:

  • Amplitude of motor evoked potential (MEP)recorded at cortex stimulation is characterized by the number of undamaged motoneurons in cortex structures.
  • Central motor conduction time (conduction time from cortex to cervical part) reveals the integrity of motor pathways.
  • Amplitude ratio (motor evoked potential/M-wave) is used to assess the excitability of motor cortex.
  • Motor evoked potential facilitation is used when the response is not obtained without facilitation. The obtained response at facilitation and missed one without facilitation can evidence high level of motoneurons and (or) pathways injury. At that the integrity of the given structures is still obvious.

All parameters are recorded separately from right and left sides.

Examples of Techniques**

Study of root conduction timeStudy of root conduction time Tripple stimulation testTripple stimulation test Study of central motor conduction timeStudy of central motor conduction time
Motor response variabilityMotor response variability

If you want to know more about the magnetic stimulation, we recommend reading the following literature:

* all techniques are implemented in Neuro-MEP.NET software supplied optionally
** screenshot of Neuro-MEP.NET software supplied optionally

Delivery set

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Updated 21.01.2015
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